This presentation will provide an overview on how economic arguments can been used to help strengthen the case for investment in policy and practice for selfharm and suicide prevention from an international perspective. It will highlight the profound economic consequences of self-harm and suicide, not only for affected individuals and their families, but for all of society. It will also examine how the evidence base on what is known about the cost effectiveness of preventive measures has grown and how this can be strengthened further, including through measures to address some of the economic pressures that can be associated with increased risk of self-harm and suicide.